Table 1.

Characteristics of both the 20 weak learner models in the development set and the 14 ensemble models in the test set for fatal and nonfatal overdose

	Fatal overdose					Nonfatal overdose
Weak learner/ensemble	AUROC	AUPRC	Cases	Controls	% Outcomes	AUROC	AUPRC	Cases	Controls	% Outcomes
WL1	0.77	0.00024	224	3 566 077	0.0063	0.79	0.0018	1131	3 580 452	0.032
WL2	0.73	0.00023				0.78	0.0016
WL3	0.76	0.00023				0.79	0.0019
WL4	0.75	0.00024				0.78	0.0016
WL5	0.72	0.00026				0.79	0.0021
WL6	0.73	0.00027				0.80	0.0019
WL7	0.71	0.00023				0.79	0.0017
WL8	0.78	0.00024				0.80	0.0017
WL9	0.75	0.00025				0.79	0.0017
WL10	0.72	0.00026				0.78	0.0015
Maximum	0.83	0.00040	963	14 316 606	0.0067	0.82	0.0014	4031	14 309 753	0.028
Minimum	0.67	0.00032				0.76	0.0014
Mean	0.83	0.00042				0.83	0.0015
Median	0.80	0.00041				0.82	0.0015
LASSO	0.79	0.00038				0.82	0.0015
Ridge	0.83	0.00042				0.83	0.0016
Random forest	0.38	0.00007				0.49	0.0004

Note: Ensemble models combined and calibrated weak learner model predictions from the development set.

AUPRC: area under the precision recall curve; AUROC: area under the receiver operating curve.