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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Curr Opin Struct Biol. 2021 Apr 6;70:16–25. doi: 10.1016/j.sbi.2021.02.007

Figure 2.

Figure 2.

A growing number of nuclei are targeted for relaxation dispersion measurements (CEST, CPMG and R1ρ) in studies of nucleic acid ESs. The list of probes is growing steadily from an initial focus on protonated carbons, imino and amino (G-N2) nitrogens (highlighted using blue circles) to now include protons, non-protonated and amino (C-N4) nitrogens, ribose C5', and nuclei in modified bases including m6A, m5C and cmo5U (highlighted using red circles). Also shown are the types of RD experiments performed for the various probes.