TABLE 1.
Summary of patient demographics and disease details
| Patient demographics (N = 100) | N (%) |
|---|---|
| Sex | |
| Male | 52 (52.0) |
| Female | 48 (48.0) |
| Age (years) | |
| Median | 6.71 |
| Range | 0.010‐20.30 |
| Patient residence | |
| Metropolitan | 50 (50.0) |
| Regional or interstate | 50 (50.0) |
| Parental country of birth | |
| Australia | 86 (86.0) |
| Other | 14 (14.0) |
| Tumor types | |
| Solid | 52 (52.0) |
| Brain | 31 (31.0) |
| Hematological | 17 (17.0) |
| Treatment line | |
| First | 16 (16.0) |
| Second | 35 (35.0) |
| Third or greater | 49 (49.0) |
| Disease state | |
| Refractory | 51 (51.0) |
| Relapsed | 29 (29.0) |
| Other | 20 (20.0) |
| Patient diagnoses | |
| Brain tumors (N = 52) | |
| LGG a | 27 (27.0) |
| HGG b | 12 (12.0) |
| Medulloblastoma/PNET | 9 (9.0) |
| Ependymoma | 2 (2.0) |
| Acoustic neuroma | 1 (1.0) |
| Glioma (unspecified) | 1 (1.0) |
| Solid tumors (N = 31) | |
| Plexiform neurofibroma | 6 (6.0) |
| Rhabdomyosarcoma | 3 (3.0) |
| LCH | 2 (2.0) |
| Osteosarcoma | 2 (2.0) |
| Hemangioma | 2 (2.0) |
| Hemangioendothelioma | 2 (2.0) |
| Anaplastic large cell lymphoma | 1 (1.0) |
| Atypical Spitz Naevus | 1 (1.0) |
| Clear cell adenocarcinoma | 1 (1.0) |
| Desmoid tumor | 1 (1.0) |
| Germ cell tumor | 1 (1.0) |
| Hepatoblastoma | 1 (1.0) |
| Kaposiform lymphangiomatosis | 1 (1.0) |
| Liposarcoma | 1 (1.0) |
| Melanoma of soft parts | 1 (1.0) |
| Non‐Hodgkin's lymphoma | 1 (1.0) |
| Non‐Langerhans histiocytosis | 1 (1.0) |
| Renal cell carcinoma | 1 (1.0) |
| Spinal Sarcoma | 1 (1.0) |
| Wilm's tumor (Kidney) | 1 (1.0) |
| Hematological (N = 17) | |
| Pre‐B ALL | 9 (9.0) |
| AML | 2 (2.0) |
| ETPLL | 2 (2.0) |
| Myelodysplastic/proliferative disorder | 2 (2.0) |
| Hypereosinophilic syndrome | 1 (1.0) |
| Biphenotypic leukemia | 1 (1.0) |
Abbreviations: AML, acute myeloid leukemia; ETPLL, early T‐cell precursor lymphoblastic leukemia; HGG, high‐grade glioma; LCH, Langerhans cell histiocytosis; LGG, low‐grade glioma; PNET, primitive neuroectodermal tumor; Pre‐B ALL, precursor B‐cell acute lymphoblastic leukemia.
a
LGG encompassed diffuse astrocytoma, disseminated glioneuronal tumor, ganglioglioma, low‐grade glioma, oligoastrocytoma, pilocytic astrocytoma and pleomorphic xanthroastrocytoma.
b
HGG encompassed glioblastoma multiforme, anaplastic astrocytoma and diffuse intrinsic pontine glioma.