TABLE 6.
Spearman partial correlation coefficient (r) for covariate‐adjusted association between clinical stage and weekly sunlight exposure, by type of retinoblastoma and time period of exposure
| Age period during which had sunlight exposure | Unilateral retinoblastoma (n = 245) | Unilateral retinoblastoma (n = 245) | Unilateral retinoblastoma (n = 245) | Bilateral retinoblastoma (n = 116) | Bilateral retinoblastoma (n = 116) | Bilateral retinoblastoma (n = 116) |
|---|---|---|---|---|---|---|
| IIRC | ISS | St. Jude | IIRC | ISS | St. Jude | |
| r a (n) | r a (n) | r a (n) | r a (n) | r a (n) | r a (n) | |
| Weekly Sunlight exposure (<6 m) | 0.110 (207) | −0.022 (100) | −0.031 (126) | 0.061 (93) | 0.079 (62) | 0.025 (74) |
| Weekly Sunlight exposure (6–11.9 m) | 0.019 (187) | −0.041 (91) | 0.051 (115) | −0.108 (71) | −0.116 (47) | 0.034 (55) |
| Weekly Sunlight Exposure (12–23.9 m) | 0.049 (160) | −0.092 (75) | −0.078 (96) | −0.254 (49)* | −0.239 (34) | −0.034 (34) |
Note: IIRC: International Retinal Classification (numerified: A = 1, B = 2, C = 3, D = 4, 5 = E); ISS: international staging system for risk of extra retinal disease (numerified) (1 = ISS1, N0; 2 = ISS1, N > 0; 3 = ISS2; 4 = ISS3; 5 = ISS4). St. Jude: St Jude or Pratt staging system for extra ocular spread (numerified as stages 1–4). *p = .089.
a
Covariates include maternal education elevation and age at diagnosis.