Skip to main content
. 2021 Dec 15;12:752557. doi: 10.3389/fimmu.2021.752557

Table 2.

Patient characteristics.

All patients Age<18 Age≥18 P value
(n = 67) (n = 25) (n = 42)
Symptoms at onset
Visual loss 24 (35.8) 9 (36.0) 15 (35.7) 0.981
Paralysis 16 (23.9) 5 (20.0) 11 (26.2) 0.636
Paresthesia 19 (28.4) 5 (20.0) 14 (33.3) 0.242
Nausea/Vomiting 7 (10.4) 6 (24.0) 1 (2.4) 0.009*
Fever 10 (14.9) 5 (20.0) 5 (11.9) 0.368
Headache 10 (14.9) 2 (8.0) 8 (19.0) 0.300
Dizziness 7 (10.4) 1(4.0) 6 (14.3) 0.244
Seizures 12 (17.9) 5 (20.0) 7 (16.7) 0.731
Speech disorders 2 (3.0) 1 (4.0) 1 (2.4) 1.000
Unsteady gait 5 (7.5) 4 (16.0) 1 (2.4) 0.061
Disturbance of consciousness 2 (3.0) 1 (4.0) 1 (2.4) 1.000
Disease spectrum
Optic neuritis 24 (35.8) 9 (36.0) 15 (35.7) 0.981
Transverse myelitis 18 (26.9) 9 (36.0) 9 (21.4) 0.193
Acute disseminated encephalomyelitis 11(16.4) 10 (40.0) 1 (2.4) 0.000*
Brainstem syndrome 11 (16.4) 4 (16.0) 7 (16.7) 1.000
Post polar syndrome 7 (10.4) 6 (24.0) 1 (2.4) 0.009*
Treatment
Corticosteroid 63 (94.0) 25 (100) 38 (90.5) 0.112
Intravenous immunoglobulin 14 (20.9) 7 (28.0) 7 (16.7) 0.270
Immunosuppressant
Azathioprine 4 (6.0) 0 4 (9.5) 0.289
Mycophenolate mofetil 3 (4.5) 1 (4.0) 2 (4.8) 1.000
Methotrexate 1 (1.4) 1 (4.0) 0 0.373
Initial EDSS 4 (2–6) 4 (3–4.75) 4 (2–6) 0.974
Discharge EDSS 2 (1–4) 1.5 (1–3) 2 (1–4) 0.351
Follow-up EDSS 1.5 (1–2) 1 (1–2) 1.5 (1–2) 0.340
Follow-up interval (months) 7 (5–15) 6 (3.5–8.5) 8 (5.375–16.75) 0.109
Relapse 14 (20.9) 6 (24.0) 8 (19.0) 0.630

Data are presented as mean ± standard deviation, number (percentage), or median (interquartile range).

EDSS, expanded disability status scale scores.

*P < 0.05.