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. 2021 Dec 15;12:752557. doi: 10.3389/fimmu.2021.752557

Table 3.

Laboratory data.

All = patients Age<18 Age≥18 P value
(n = 67) (n = 25) (n = 42)
Leukocyte counts (×109/L) 9563 ± 5.84 11.64 ± 8.26 8.36 ± 3.30 0.068
Erythrocyte counts (×1012/L) 4.39 ± 0.49 4.48 ± 0.41 4.33 ± 0.52 0.233
Hemoglobin (g/L) 128 (118.1–142.9) 124 (119.85–135) 132 (118–144.35) 0.218
Lymphocyte count (×109/L) 1.96 ± 0.99 2.14 ± 1.19 1.86 ± 0.86 0.268
Glucose (mmol/L) 4.93 ± 1.12 5.02 ± 1.20 4.88 ± 1.09 0.612
Total protein (g/L) 66.63 ± 5.99 68.81 ± 4.77 65.33 ± 6.31 0.013*
Total bilirubin (μmol/L) 8.00 ± 4.65 6.0 ± 2.19 9.19 ± 5.30 0.001*
Uric acid (μmol/L) 257.61 ± 84.72 246.60 ± 100.54 264.17 ± 74.28 0.452
Creatinine (μmol/L) 54.51 ± 16.44 41.96 ± 15.96 61.98 ± 11.53 0.000*
Total cholesterol (mmol/L) 3.79 ± 0.96 3.57 ± 0.45 3.92 ± 1.10 0.114
Triglycerides (mmol/L) 1.23 ± 0.82 1.21 ± 0.66 1.24 ± 0.91 0.892
High-density lipoprotein (mmol/L) 1.19 ± 0.32 1.17 ± 0.25 1.20 ± 0.36 0.687
Low-density lipoprotein (mmol/L) 2.29 ± 0.72 2.07 ± 0.53 2.42 ± 0.80 0.055
ESR (mm/h) 10 (6–17) 11 (6–16.5) 8.65 (5.875–18.25) 0.484
CRP (mg/L) 1.82 (0.5–4.7) 1 (0.425–5.23) 2.705 (0.975–4.385) 0.248
FT3 (pmol/L) 4.88 ± 0.97 5.04 ± 1.15 4.78 ± 0.85 0.323
FT4 (pmol/L) 13.06 ± 2.86 13.59 ± 2.73 12.74 ± 2.92 0.243
TSH (pmol/L) 2.02 ± 1.35 1.68 ± 1.11 2.22 ± 1.45 0.114
Homocysteine levels (μmol/L) 14.74 ± 6.30 15.31 ± 6.56 14.40 ± 6.19 0.574
Folic acid (ng/mL) 7.59 ± 4.02 6.60 ± 3.21 8.19 ± 4.36 0.119
Vitamin B12 (pg/mL) 591.76 ± 397.33 614.66 ± 367.69 578.14 ± 417.72 0.719
ANAs positive 17 (25.4) 3 (12.0) 14 (33.3) 0.081
Thyroid peroxidase/Thyroglobulin antibodies positive 7 (10.4) 3 (12.0) 4 (9.5) 1.000
Intracranial pressure (mmH2O) 160 (135–180) 150 (135–170) 165 (140–200) 0.048*
CSF leukocyte counts (×106/L) 12 (4–32) 15 (4.5–42) 11 (3.75–30.5) 0.266
CSF protein concentration (mg/L) 309.8 (233.2–388.9) 238 (183.55–306) 361.15 (294.525–446.875) 0.000*
Positive oligoclonal band 8 (11.9) 5 (20.0) 3 (7.1) 0.138
CSF anti-NMDAR(+) 3 (.4.5) 1 (4.0) 2 (4.8) 1.000
Serum AQP4-IgG(+) 0 0 0

Data are presented as mean ± standard deviation, number (percentage), or median (interquartile range).

NLR, neutrophil-to-lymphocyte ratio; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid-stimulating hormones; ANAs, antinuclear antibodies; CSF, cerebrospinal fluid; anti-NMDAR, anti-N-methyl-D-aspartate receptor; AQP4-IgG, aquaporin-4 immunoglobulins G.

*P < 0.05.