Table 5.
Laboratory data according to initial Expanded Disability Status Scale.
| EDSS ≤3 | EDSS>3 | P value | |
|---|---|---|---|
| (n = 28) | (n = 39) | ||
| Age at onset, years | 24.43 ± 16.52 | 27.87 ± 19.43 | 0.450 |
| Sex, female | 14 (50.0) | 20 (51.3) | 0.918 |
| Leukocyte count (×109/L) | 10.91± 7.83 | 8.64 ± 3.68 | 0.118 |
| Erythrocyte count (×1012/L) | 4.39 ± 0.59 | 4.39 ± 0.41 | 0.950 |
| Hemoglobin (g/L) | 126.85 (116.5–145.775) | 128 (122–142) | 0.652 |
| Lymphocyte count (×109/L) | 1.82 ± 0.73 | 2.07 ± 1.14 | 0.325 |
| Glucose (mmol/L) | 4.73 ± 1.00 | 5.08 ± 1.20 | 0.219 |
| Total protein (g/L) | 66.82 ± 6.30 | 66.49 ± 5.84 | 0.830 |
| Total bilirubin (μmol/L) | 7.41 ± 2.86 | 8.42 ± 5.59 | 0.335 |
| Uric acid (μmol/L) | 209.96 ± 77.03 | 291.82 ± 73.32 | 0.000* |
| Creatinine (μmol/L) | 54.93 ± 16.62 | 54.21 ± 16.53 | 0.861 |
| Total cholesterol (mmol/L) | 3.61 ± 0.75 | 3.92 ± 1.08 | 0.188 |
| Triglycerides (mmol/L) | 1.13 ± 0.87 | 1.30 ± 0.78 | 0.404 |
| High-density lipoprotein (mmol/L) | 1.18 ± 0.33 | 1.19 ± 0.31 | 0.955 |
| Low-density lipoprotein (mmol/L) | 2.05 ± 0.50 | 2.46 ± 0.81 | 0.013* |
| ESR (mm/h) | 8 (5.1–16.5) | 10 (7–18) | 0.184 |
| CRP (mg/L) | 1.585 (0.625–3.7725) | 2.31 (0.5–5.14) | 0.736 |
| FT3 (pmol/L) | 4.82 ± 0.83 | 4.92 ± 1.06 | 0.670 |
| FT4 (pmol/L) | 12.93 ± 2.60 | 13.15 ± 3.06 | 0.757 |
| TSH (pmol/L) | 1.85 ± 1.33 | 2.14 ± 1.37 | 0.389 |
| Homocysteine levels (μmol/L) | 12.56 ± 4.37 | 16.31 ± 7.02 | 0.015* |
| Folic acid (ng/mL) | 7.69 ± 3.54 | 7.52 ± 4.38 | 0.867 |
| Vitamin B12 (pg/mL) | 487.83 ± 181.10 | 666.38 ± 486.52 | 0.069 |
| ANAs positive | 6 (15.4) | 11 (28.2) | 0.530 |
| Thyroid peroxidase/Thyroglobulin antibodies positive | 2 (5.1) | 5 (12.8) | 0.454 |
| Intracranial pressure (mmH2O) | 160 (126.25–180) | 160 (140–175) | 0.592 |
| CSF leukocyte counts (×106/L) | 10 (4–27.75) | 14 (4–40) | 0.511 |
| CSF protein concentration (mg/L) | 309.6 (226.75–369.175) | 309.8 (238–440.2) | 0.457 |
Data are presented as mean ± standard deviation, number (percentage), or median (interquartile range).
NLR, neutrophil-to-lymphocyte ratio; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid-stimulating hormones; ANAs, antinuclear antibodies; CSF, cerebrospinal fluid; EDSS, Expanded Disability Status Scale.
*P < 0.05.