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. 2021 Dec 15;13:758236. doi: 10.3389/fnagi.2021.758236

TABLE 4.

Abnormal white matter tracts derived from DKI different parameters in the LPI group.

Group Parameters Cluster index Cluster size (voxels) MNI coordinates Minimally P-values White matter tracts
LPI FADKI 1 47,944 91 0.001 23 0.001 MCP, PCT, Genu of CC, Body of CC, Splenium of CC, FX, CST_R, CST_L, ML_R, ML_L, ICP_R, ICP_L, SCP_R, SCP_L, CP_R, CP_L, ALIC_R, ALIC_L, PLIC_R, PLIC_L, RLIC_R, RLIC_L, ACR_R, ACR_L, SCR_R, SCR_L, PCR_R, PCR_L, PTR_R, PTR_L, SS_R, SS_L, EC_R, EC_L, CG_R, CG_L, ST_R, ST_L, SLF_R, SLF_L, SFO_R, UNC_R, UNC_L, TAP_R
MDDKI 1 55,715 99 156 156 0.001 MCP, PCT, Genu of CC, Body of CC, Splenium of CC, FX, CST_R, CST_L, ML_R, ML_L, ICP_R, ICP_L, SCP_R, SCP_L, CP_R, CP_L, ALIC_R, ALIC_L, PLIC_R, PLIC_L, RLIC_R, RLIC_L, ACR_R, ACR_L, SCR_R, SCR_L, PCR_R, PCR_L, PTR_R, PTR_L, SS_R, SS_L, EC_R, EC_L, ST_R, ST_L, SLF_R, SLF_L, SFO_R, UNC_L
RDDKI 1 66462 96 76 23 0.001 MCP, PCT, Genu of CC, Body of CC, Splenium of CC, FX, CST_R, CST_L, ML_R, ML_L, ICP_R, ICP_L, SCP_R, SCP_L, CP_R, CP_L, ALIC_R, ALIC_L, PLIC_R, PLIC_L, RLIC_R, RLIC_L, ACR_R, ACR_L, SCR_R, SCR_L, PCR_R, PCR_L, PTR_R, PTR_L, SS_R, SS_L, EC_R, EC_L, CG_R, CG_L, ST_R, ST_L, SLF_R, SLF_L, SFO_R, UNC_R, UNC_L, TAP_R
MK DKI 1 191 112 109 72 0.009 PLIC_L
2 617 111 98 115 0.005 ACR_L, SCR_L, PCR_L, SLF_L

LPI, left pontine infarction; FA, fractional anisotropy; MD, mean diffusivity; RD, radial diffusivity; MK, mean kurtosis; DKI, Diffusion Kurtosis Imaging; MCP, Middle cerebellar peduncle; PCT, Pontine crossing tract (a part of MCP); Genu of CC, Genu of corpus callosum; Body of CC, Body of corpus callosum; Splenium of CC, Splenium of corpus callosum; FX, Fornix (column and body of fornix); CST_R, Corticospinal tract R; CST_L, Corticospinal tract L; ML_R, Medial lemniscus R; ML_L, Medial lemniscus L; ICP_R, Inferior cerebellar peduncle R; ICP_L, Inferior cerebellar peduncle L; SCP_R, Superior cerebellar peduncle R; SCP_L, Superior cerebellar peduncle L; CP_R, Cerebral peduncle R; CP_L, Cerebral peduncle L; ALIC_R, Anterior limb of internal capsule R; ALIC_L, Anterior limb of internal capsule L; PLIC_R, Posterior limb of internal capsule R; PLIC_L, Posterior limb of internal capsule L; RLIC_R, Retrolenticular part of internal capsule R; RLIC_L, Retrolenticular part of internal capsule L; ACR_R, Anterior corona radiata R; ACR_L, Anterior corona radiata L; SCR_R, Superior corona radiata R; SCR_L, Superior corona radiata L; PCR_R, Posterior corona radiata R; PCR_L, Posterior corona radiata L; PTR_R, Posterior thalamic radiation (include optic radiation) R; PTR_L, Posterior thalamic radiation (include optic radiation) L; SS_R, Sagittal stratum (include inferior longitudinal fasciculus and inferior fronto_occipital fasciculus) R; SS_L, Sagittal stratum (include inferior longitudinal fasciculus and inferior fronto_occipital fasciculus) L; EC_R, External capsule R; EC_L, External capsule L; CG_R, Cingulum (cingulate gyrus) R; CG_L, Cingulum (cingulate gyrus) L; ST_R, Fornix (cres) / Stria terminalis R; ST_L, Fornix (cres) / Stria terminalis L; SLF_R, Superior longitudinal fasciculus R; SLF_L, Superior longitudinal fasciculus L; SFO_R, Superior fronto_occipital fasciculus (could be a part of anterior internal capsule) R; UNC_R, Uncinate fasciculus R; UNC_L, Uncinate fasciculus L; TAP_R, Tapetum R.