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Flowchart of the macular vascular geometry assessment according to Early Treatment Diabetic Retinopathy Study (ETDRS). The fundus photograph (A) was pre-processed and input to the dense block generative adversarial network (D-GAN) segmentation system, exporting a binarized retinal vascular network map (B), and further analyzed to quantify the macular vascular geometry based on ETDRS (C).
