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. 2021 Nov 3;321(6):R912–R924. doi: 10.1152/ajpregu.00004.2021

Table 1.

Effects of early-onset hypoxia on fetal and placental weights of males and females

Early-Onset HPX
Males
Females
NMX EO-HPX NMX EO-HPX
Fetal parameters
n values 11 8 10 8
Absolute Wt
 FBW, g 89.0 ± 3.8 76.7 ± 4.0* 92.5 ± 4.5 79.4 ± 5.1
 FHt, g 0.54 ± 0.03 0.49 ± 0.03 0.54 ± 0.02 0.45 ± 0.03*
 FBr, g 2.60 ± 0.04 2.62 ± 0.03 2.58 ± 0.05 2.59 ± 0.06
 FLiv, g 4.51 ± 0.46 3.65 ± 0.43 4.66 ± 0.44 3.70 ± 0.33
 FKid, g 0.42 ± 0.02 0.34 ± 0.02* 0.47 ± 0.03 0.33 ± 0.02*
 Plac Wt, g 4.42 ± 0.32 5.06 ± 0.21 4.62 ± 0.26 4.78 ± 0.35
Relative Wt
 FHt/FBW 0.0060 ± 0.0002 0.0064 ± 0.0002 0.0059 ± 0.0002 0.0057 ± 0.0003
 FBr/FBW 0.0295 ± 0.0012 0.0347 ± 0.0002* 0.0283 ± 0.0012 0.0334 ± 0.0019*
 FLiv/FBW 0.0499 ± 0.003 0.0468 ± 0.0030 0.0501 ± 0.003 0.0462 ± 0.0014
 FKid/FBW 0.0047 ± 0.0001 0.0044 ± 0.0002 0.0051 ± 0.0003 0.0042 ± 0.0001*
 Plac/FBW 0.049 ± 0.002 0.067 ± 0.003* 0.050 ± 0.002 0.060 ± 0.002*

Comparisons between treatment (NMX vs. HPX) in males and females were made using two-way ANOVA with statistical significance (*P < 0.05) indicated by an asterisk to indicate difference from its respective NMX control. EO-HPX, early-onset hypoxia; FBr, fetal brain; FBW, fetal body weight; FHt, fetal heart; FKid, fetal kidney; FLiv, fetal liver; NMX, normoxia; plac, placenta; Wt, weight.