Table 2.
Effects of late-onset hypoxia on fetal and placental weights of males and females
| Late-Onset HPX | ||||
|---|---|---|---|---|
| Males |
Females |
|||
| NMX | LO-HPX | NMX | LO-HPX | |
| Fetal parameters | ||||
| n values | 11 | 8 | 10 | 8 |
| Absolute Wt | ||||
| FBW, g | 89.0 ± 3.8 | 79.8 ± 4.1 | 92.5 ± 4.5 | 77.6 ± 4.6* |
| FHt, g | 0.54 ± 0.03 | 0.43 ± 0.02* | 0.54 ± 0.02 | 0.44 ± 0.03* |
| FBr, g | 2.60 ± 0.04 | 2.46 ± 0.07 | 2.58 ± 0.05 | 2.43 ± 0.06* |
| FLiv, g | 4.51 ± 0.46 | 4.02 ± 0.30 | 4.66 ± 0.44 | 4.08 ± 0.33 |
| FKid, g | 0.42 ± 0.02 | 0.40 ± 0.02 | 0.47 ± 0.03 | 0.39 ± 0.02* |
| Plac Wt, g | 4.42 ± 0.32 | 4.88 ± 0.46 | 4.62 ± 0.26 | 4.52 ± 0.39 |
| Relative Wt | ||||
| FHt/FBW | 0.0060 ± 0.0002 | 0.0054 ± 0.0002* | 0.0059 ± 0.0002 | 0.0057 ± 0.0002 |
| FBr/FBW | 0.0295 ± 0.0012 | 0.0313 ± 0.0002 | 0.0283 ± 0.0012 | 0.0318 ± 0.0013 |
| FLiv/FBW | 0.0499 ± 0.003 | 0.0501 ± 0.0020 | 0.0501 ± 0.003 | 0.0524 ± 0.0024 |
| FKid/FBW | 0.0047 ± 0.0001 | 0.005 ± 0.0002 | 0.0051 ± 0.0003 | 0.005 ± 0.0001 |
| Plac/FBW | 0.049 ± 0.002 | 0.061 ± 0.004* | 0.050 ± 0.002 | 0.058 ± 0.002* |
Comparisons between treatment (NMX vs. HPX) in males and females were made using two-way ANOVA with statistical significance (*P < 0.05) indicated by an asterisk to indicate difference from its respective NMX control. FBr, fetal brain; FBW, fetal body weight; FHt, fetal heart; FKid, fetal kidney; FLiv, fetal liver; LO-HPX, late-onset hypoxia; NMX, normoxia; plac, placenta; Wt, weight.