Table 2.
Patient demographics upon enrollment
| Parameter (allowed; units) | Median (range) |
|---|---|
| Age (18-65 years) | 47 (22–57) |
| Gender (male/female) | N/A (9 M/8 F) |
| Weight (kg) | 79.5 (53.5–104) |
| Years T1D (>5 years) | 37 (8–52) |
| Insulin usage (units/day) | 36.5 (11.1–96.6) |
| Glucose AUC (ng/mL) | 940 (314a–1388) |
| HbA1c (< 10%) | 7.1 (5.9–9.0) |
| Hypoglycemia unawareness (Clarke score >4) | 5 (4–7) |
| Time in range % (70–180 mg/dL) | 60 (37–77) |
| Time above range % (>180 mg/dL) | 34 (19-61) |
| Time below range % (<70 mg/dL) | 5 (1–15) |
| Hypoglycemic events (patient-reported <70 mg/dL; 7-day total) | 2 (0–17) |
a
One subject’s glucose values were available for analysis only through t = 90 min for the 4 h MMTT.