Figure 4.

Identifying the major contributors to atrophy-centered subtyping of MCI via occlusion analysis

(A) Schematic illustration of the occlusion analysis. The testing phase in the deep learning model was repeated, whereby in each step cortical lobes were occluded from the input data (temporal lobes were further divided to medial and lateral). The percentages of change with respect to the original results for classifying MCI subgroups were ranked.

(B) The results of the occlusion analysis are shown, in each tested lobe. Shown are percentages of change with respect to the original intact model.

(C) Percentage of change following occlusion analysis, in each cortical lobe, superimposed on medial and lateral cortical surface models.

MCI, mild cognitive impairment.