Table 6.
Multivariate analysis of predictors of a tumour-free clinical outcome.
Parameters | OR | 95%CI | P |
---|---|---|---|
Sex | |||
Male | 1 | ||
Female | 0.355 | 0.111–1.135 | 0.081 |
Surgery | |||
TT+ central neck lymph node dissection | 1 | ||
TT+ central and lateral neck lymph node dissection | 0.677 | 0.139–3.288 | 0.628 |
Extrathyroidal extension | |||
No invasion | 1 | ||
Microscopic | 1.703 | 0.097–29.976 | 0.716 |
Macroscopic | 0.890 | 0.061–13.048 | 0.932 |
T | |||
T1 | 1 | ||
T2 | 0.016 | 0.000–0.876 | 0.043 |
T3 | 0.060 | 0.001–3.207 | 0.166 |
T4 | 0.247 | 0.012–5.162 | 0.367 |
N | |||
N0 | 1 | ||
N1a | 0.820 | 0.100–6.732 | 0.854 |
N1b | 1.120 | 0.212–5.925 | 0.894 |
Initial risk stratification | |||
Low risk | 1 | ||
Intermediate risk | 0.283 | 0.025–3.234 | 0.310 |
High risk | 0.461 | 0.124–1.712 | 0.247 |
The variation of TgAb relative to preoperative level | |||
Before 131I therapy <−63.4% | 1 | ||
Before 131I therapy ≥−63.4% | 0.600 | 0.193–1.865 | 0.377 |
6 months after 131I therapy <−77.9% | 1 | ||
6 months after 131I therapy ≥−77.9% | 3.098 | 0.975–9.845 | 0.055 |
1 year after 131I therapy <−77.4% | 1 | ||
1 year after 131I therapy ≥−77.4% | 4.875 | 1.651–14.395 | 0.004 |
2 years after 131I therapy <−88.6% | 1 | ||
2 years after 131I therapy ≥−88.6% | 9.919 | 3.185–30.885 | <0.001 |
OR, odds ratio; TT, total thyroidectomy; TgAb, antithyroglobulin antibody.