FIGURE 8.

YZFDF promoted Aβ clearance and prevented the formation of Aβ_1-42 oligomers at 24 h after cerebral I/R in rats. (A,B) Representative pictures of double immunofluorescence staining of Aβ (red) with GFAP (green) in cortex and hippocampus-CA1 areas, and white arrows represent Aβ accumulation in sites of swelling astrocytic endfeet, scale bars = 50 and 20 μm, as shown in pictures. (C) Quantitative analysis of relative Aβ density in the cortex (scale bar = 50 μm), n = 3. (D) Representative Western blots for the Aβ_1-42 monomer and Aβ_1-42 oligomer. (E) Quantitative analysis of Aβ_1-42 oligomers, n = 6. ^## p < 0.01 vs. Sham group; ^** p < 0.01 vs. I/R group.