Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 15;13:758895. doi: 10.3389/fnagi.2021.758895

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Chiang, Lin, Teng, Sun, Chang, Lin, Hsieh-Li, Su, Chen and Lee-Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Molecular targets of 7,8-DHF, quercetin, and apigenin in SH-SY5Y cells expressing ΔK280 Tau_RD-DsRed. Congo red (10 μM) was included as a negative control. Relative TRKB, p-TRKB (Y817), p-TRKB/TRKB, extracellular signal-regulated kinase (ERK), p-ERK (T202/Y204), cAMP-response element binding protein (CREB), p-CREB (S133), BCL2 apoptosis regulator (BCL2), and BCL2-associated X protein (BAX) protein levels were analyzed through immunoblotting using specific antibodies (n = 3). GAPDH was used as a loading control. Relative protein levels are shown on the right side of the representative western blot images. To normalize, the relative protein level in uninduced cells (Dox -) was set as 100%. p-values: comparisons between induced and uninduced cells (^#p < 0.05) or between treated and untreated cells (*p < 0.05, **p < 0.01, ***p < 0.001) (one-way ANOVA with the post hoc Tukey’s test).