Immunoglobulin occurs in a kidney intrinsic manner
(A) Schematic demonstrating experiment design testing kidney-intrinsic predisposition to kidney disease.
(B) Immunofluorescence of immunoglobulin G (red), podocin (green) and DAPI in cryosections from 8-week-old mice of B cell deficient Vangl1+/− and Vangl1+/+ mice injected with IgG.
(C) Scoring of immunofluorescent IgG deposition in mice post injection. Data are represented as median, Mann-Whitney U, p = 0.02.