Table 1.
Demographics of patient cohorts
| Clinical | HC n = 11 | SS n = 11 | SLE 1 n = 55 | SLE 2 n = 177 | SLE 3 n = 281 |
|---|---|---|---|---|---|
| Age (years) (IQR) | 57 (56-66 years) | 48 (45-51 years) | 50 (35-60 years) | 47 (35-60 years) | |
| Gender (female) (%) | 6 (55%) | 11 (100%) | 49 (89%) | 148 (83%) | 253 (90%) |
| Oral ulcers (%) | 0 | 0 | 13 (24%) | 53 (30%) | 73 (26%) |
| Arthritis (%) | 0 | 0 | 38 (69%) | 122 (69%) | 204 (72%) |
| Raynaud’s (%) | 0 | 0 | 19 (35%) | 60 (34%) | Unknown |
| Cutaneous (%) | 0 | 0 | 30 (55%) | 99 (56%) | 153 (54%) |
| Nephritis (%) | 0 | 0 | 23 (42%) | 62 (35%) | 113 (40%) |
| Serositis (%) | 0 | 0 | 15 (27%) | 41 (23%) | 91 (32%) |
| Alopecia (%) | 0 | 0 | 7 (13%) | 39 (22%) | Unknown |
| Seizure (%) | 0 | 0 | 9 (16%) | 20 (11%) | 9 (3%) |
| Sicca (%) | 0 | 11 (100%) | 15 (27%) | 62 (35%) | Unknown |
| Myositis (%) | 0 | 0 | 0 | 7 (4%) | Unknown |
| Cytopaenia (%) | 0 | 0 | 28 (51%) | 76 (43%) | 178 (63%) |
| Antiphospholipid Ab (%) | 0 | 0 | 27 (49%) | 78 (44%) | Unknown |
| ANAs (%) | 0 | 10 (91%) | 55 (100%) | 177 (100%) | 257 (91%) |
| dsDNAs (%) | 0 | 0 | 44 (80%) | 112 (63%) | 159 (56%) |
| Anti-Sm (%) | 0 | 0 | 8 (15%) | 21 (12%) | 31 (11%) |
| Hypocomplementemia (%) | 0 | 0 | 36 (65%) | 76 (43%) | Unknown |