Table 2.
Blood measurements on a high-K+ diet
| γ +/+ | γmt/mt | Male γ+/+ | Male γmt/mt | Female γ+/+ | Female γmt/mt | |
|---|---|---|---|---|---|---|
| Na+, mmol/L | 146 ± 3 (15) | 147 ± 2 (13) | 148 ± 2 (8) | 148 ± 2 (9) | 145 ± 4 (7) | 145 ± 2 (4) |
| K+, mmol/L | 5.1 ± 0.9 (15) | 5.3 ± 0.7 (13) | 5.2 ± 1.1 (8) | 5.6 ± 0.6 (9) | 5.1 ± 0.6 (7) | 4.8 ± 0.5 (4) |
| Cl−, mmol/L | 120 ± 5 (115) | 119 ± 6 (13) | 119 ± 5 (8) | 120 ± 3 (9) | 120 ± 5 (7) | 116 ± 9 (4) |
| Total CO2, mmol/L | 20 ± 2 (15) | 21 ± 4 (13) | 21 ± 3 (8) | 21 ± 2 (9) | 19 ± 1 (7) | 22 ± 7 (4) |
| Urea nitrogen, mg/dL | 26 ± 4 (15) | 29 ± 5 (13) | 28 ± 2 (8) | 29 ± 4 (9) | 24 ± 6 (7) | 28 ± 8 (4) |
| Hemoglobin, mg/dL | 13.1 ± 1.0 (14) | 13.9 ± 1.2 (13) | 13.2 ± 1.1 (8) | 13.8 ± 0.7 (9) | 13.0 ± 1.1 (7) | 14.0 ± 2.1 (4) |
| Creatinine, mg/dL | <0.2 (15) | <0.2 (13) | <0.2 (8) | <0.2 (9) | <0.2 (7) | <0.2 (4) |
Data are presented as means ± SD; numbers of mice are shown in parentheses. Twelve- to sixteen-week-old mice were given a high-K+ diet (5.2% K+ as KCl) for 10 days. Electrolytes, urea nitrogen, hemoglobin, and creatinine were assayed in whole blood. Creatinine values were all below the detection threshold. Differences were assessed using a two-tailed Student’s t test.