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. 2021 Oct 21;131(6):1691–1700. doi: 10.1152/japplphysiol.00400.2021

Table 1.

Pulmonary ventilation and gas exchange at rest and during the 4th minute of cycle exercise

  Rest
50 W
75 W
100 W
Intensity
Nitrate
Interaction
80% Wpeak
PLA DNS PLA DNS PLA DNS PLA DNS P P P PLA DNS
e, L/min 14.8 ± 0.6 15.0 ± 0.5 35.5 ± 0.9 35.2 ± 1.2 35.5 ± 0.9 35.2 ± 1.2 44.4 ± 1.3 45.3 ± 1.4 < 0.001 0.801 0.473 146.1 ± 5.3 143.7 ± 5.2
ƒB, breaths/min 16.9 ± 1.9 16.7 ± 1.1 24.3 ± 1.1 25.1 ± 1.2 26.5 ± 1.3 27.3 ± 1.2 28.8 ± 1.5 28.9 ± 1.2 < 0.001 0.291 0.599 53.3 ± 1.9 54.4 ± 1.9
t, L/min 1.04 ± 0.07 1.06 ± 0.08 1.51 ± 0.06 1.46 ± 0.05 1.74 ± 0.06 1.71 ± 0.06 1.97 ± 0.07 1.96 ± 0.07 < 0.001 0.332 0.592 2.76 ± 0.10 2.67 ± 0.12
o2, L/min 0.37 ± 0.01 0.38 ± 0.01 1.18 ± 0.02 1.13 ± 0.03 1.45 ± 0.03 1.42 ± 0.03 1.70 ± 0.04 1.71 ± 0.03 < 0.001 0.19 0.226 3.15 ± 0.15 3.14 ± 0.16
o2, % of max 12 ± 1 12 ± 1 37 ± 2 35 ± 2 45 ± 2 45 ± 2 53 ± 3 55 ± 3 97 ± 2 96 ± 2
co2, L/min 0.27 ± 0.01 0.27 ± 0.01 0.91 ± 0.03 0.89 ± 0.03 1.19 ± 0.03 1.16 ± 0.03 1.48 ± 0.04 1.45 ± 0.04 < 0.001 0.153 0.706 3.05 ± 0.12 2.93 ± 0.13*
RER 0.74 ± 0.02 0.74 ± 0.03 0.77 ± 0.02 0.77 ± 0.01 0.83 ± 0.02 0.81 ± 0.01 0.86 ± 0.02 0.85 ± 0.02 < 0.001 0.335 0.787 0.98 ± 0.02 0.94 ± 0.02
e/ V̇o2, L/min 41.4 ± 3.4 40.3 ± 3.3 27.6 ± 0.8 28.5 ± 0.7 27.9 ± 0.6 29.2 ± 0.9 29.5 ± 1.0 29.9 ± 0.9 0.013 0.12 0.604 43.7 ± 1.7 43.2 ± 1.6
e/ V̇co2, L/min 51.4 ± 3.7 51.2 ± 3.4 35.8 ± 1.2 37.4 ± 1.1 33.9 ± 0.6 35.9 ± 0.9 34.4 ± 0.8 35.3 ± 0.9 0.027 0.042 0.474 45.0 ± 1.3 45.9 ± 1.7

DNS, dietary nitrate supplementation; ƒB, breathing frequency; PLA, placebo; V̇E, minute ventilation; V̇t, tidal volume; V̇co2, carbon dioxide production; V̇o2, oxygen consumption. *P < 0.05 vs. PLA. n = 11.