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Measurements of plasma insulin levels in selected cohorts of mice (n=5–6 mice/group). (A) * = Three-Way ANOVA for genotype and treatment (Bonferroni): *p < 0.05, **p < 0.001, ***p < 0.0001. (B) Comparisons of plasma insulin levels by genotype (panels i-iv) and age (panels v-viii). * = Student's t-test: *p < 0.05, **p < 0.001, ***p < 0.0001. Error bars represent the SEM.
