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. 2021 Oct 30;120(23):5243–5254. doi: 10.1016/j.bpj.2021.10.037

Table 2.

MIC for different bacterial strains with different agents

Agent VH1000 JCW154 MSG192 MG1655 JCW10 SM7 MDG196
MM-CH copolymer (μg/mL) 25 25 25 25 25 25 25
MM homopolymer (μg/mL) 31 31 31 31 31 31 31
LL-37 (μM) 4 4 4 4 4 4 4
Cecropin A (μM) 2 2 2 2 2 2 2
DM-DMCP copolymer (μg/mL) 12.5 12.5 12.5 12.5 12.5
DM-DMCH copolymer (μg/mL) 12.5 12.5 12.5 12.5 12.5

Note that MIC is measured in μΜ for the two chemically defined AMPs, but in μg/mL for the polymers, which lack a well-defined molecular weight. From the known molecular weights of the natural AMPs, for LL-37 we can convert MIC = 4 μM = 18 μg/mL; for cecropin A, MIC = 2 μM = 8 μg/mL. When expressed in μg/mL, all the MIC values lie in a fairly narrow range from 8 to 31 μg/mL.