Table 2.
Agent | VH1000 | JCW154 | MSG192 | MG1655 | JCW10 | SM7 | MDG196 |
---|---|---|---|---|---|---|---|
MM-CH copolymer (μg/mL) | 25 | 25 | 25 | 25 | 25 | 25 | 25 |
MM homopolymer (μg/mL) | 31 | 31 | 31 | 31 | 31 | 31 | 31 |
LL-37 (μM) | 4 | 4 | 4 | 4 | 4 | 4 | 4 |
Cecropin A (μM) | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
DM-DMCP copolymer (μg/mL) | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | – | – |
DM-DMCH copolymer (μg/mL) | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | – | – |
Note that MIC is measured in μΜ for the two chemically defined AMPs, but in μg/mL for the polymers, which lack a well-defined molecular weight. From the known molecular weights of the natural AMPs, for LL-37 we can convert MIC = 4 μM = 18 μg/mL; for cecropin A, MIC = 2 μM = 8 μg/mL. When expressed in μg/mL, all the MIC values lie in a fairly narrow range from 8 to 31 μg/mL.