Figure 3.

From single to multiple populations

Scatterplot showing number of genes with ${\text{log}}_{10}$ BF $\ge$ 5 for white British population only (x axis) versus meta-analysis (y axis) across 35 biomarkers. Assuming that BFs are correctly calibrated in both analyses and that meta-analysis is not inflated compared to white British-only MRP, this figure suggests a 26% increase in power when incorporating summary statistics across multiple populations.