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. 2021 Nov 23;120(24):5438–5453. doi: 10.1016/j.bpj.2021.11.2886

Figure 4.

Figure 4

Raw data and results obtained from fitting the model based on unshifted pKa values versus the full model—Eq. 6—to the profile of net charge versus pH obtained from potentiometric titrations. Panel A shows results for (E4K4)1; Panel B shows results for (E4K4)2 and panel (C) shows results for (E4K4)3. (D) A comparison of the fitted profiles for the three peptides. To enable these comparisons, the ordinate is rescaled to be normalized by the magnitude of the maximal charge realizable for each system.