Figure 11.

(A) Entrained spontaneous activity in a chain of 30 cardiac myocytes, with adjacent cells coupled via a common diffusion-limited cleft domain w = 8 nm and high fractional potassium cleft current F_IK1 = 0.8. (B) Intracellular potential V_i, (C) cleft potential V_cl, (D) cleft inward rectifier potassium current I_K1, (E) junctional potential V_j, (F) lateral membrane sodium current I current, (G) cleft potassium concentration K, (H) lateral membrane L-type calcium current $I_{C{a}_{cl}}$, and (I) cleft K+ reversal potential $E_{K_{cl}}$ are shown as a function of time for the middle cell or cleft, respectively. Supporting materials and methods LRd_EpC_Automaticity.zip contains the MATLAB source code.