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. 2021 Nov 23;64(1):e74. doi: 10.1192/j.eurpsy.2021.2252

Table 4.

Multivariable models for clinical outcomes.

Factor OR or Slope (β) [95%CI] χ2 or t-Score p-Value
Diagnosis: BD > MDDa
Higher cyc 1.14 [1.09–1.20] 25.4 <0.0001
Lower anx 0.775 [0.686–0.875] 16.9 <0.0001
Lower dys 0.859 [0.797–0.926] 15.6 <0.0001
Higher irr 1.10 [1.01–1.19] 4.97 0.029
%-Time [Hypo]manicb
Lower anx −0.875 [−1.58 to −0.169] 2.43 0.015
Higher cyc 0.325 [0.045–0.606] 2.28 0.023
Higher hyp 0.442 [0.053–0.831] 2.23 0.026
Higher irr 0.517 [0.039–0.995] 2.12 0.034
%-Time depressedb
Higher dys 1.49 [0.670–2.31] 3.57 <0.0001
Substance abusea
Higher irr 1.30 [1.20–1.43] 36.5 <0.0001
BD > MDD 2.26 [1.60–3.20] 21.2 <0.0001
Lower anx 0.766 [0.662–0.887] 12.7 0.0004
Suicidal actsa
BD > MDD 2.49 [1.70–3.64] 22.0 <0.0001
Higher dys 1.14 [1.04–1.25] 7.62 0.006
Lower hyp 0.893 [0.816–0.977] 6.13 0.013
Higher irr 1.13 [1.02–1.24] 5.94 0.015

Note: Lower hyp scores with suicidal acts or ideation were found in preliminary bivariate analyses with both BD and MDD subjects, but selectively with BD for suicidal acts (Table 3 ).

Abbreviations: anx, anxious temperament; BD, bipolar disorder; cyc, cyclothymic temperament; dys, dysthymic temperament; hyp, hyperthymic temperament; irr, irritable temperament; MDD, major depressive disorder.

a

Logistic regression modeling (OR).

b

Linear regression modeling (slope).