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. Author manuscript; available in PMC: 2021 Dec 29.
Published in final edited form as: Int J Infect Dis. 2021 Sep 10;112:205–211. doi: 10.1016/j.ijid.2021.09.010

Figure 2. Performance of IGRA and TST is inconsistent during peripartum.

Figure 2.

Qualitative performance of an interferon gamma release assay (IGRA) and tuberculin skin test (TST) at each pregnancy stage in a longitudinal cohort of initially IGRA+ pregnant women with and without HIV in Pune, India (n=165)., IGRA performance declined at delivery, characterized by lowest IGRA positivity (proportion ≥0.35IU/mL) and highest rate of indeterminant results (nil >8.0IU/mL or mitogen <0.50IU/mL); IGRA positivity did not differ significantly according to HIV status, although women without HIV tended to remain IGRA+ at delivery (p=0.07. IGRA+/TST+ concordance was particularly low among women living with HIV compared to those without HIV (p=0.003); TST positivity improved at delivery and 6 months postpartum with no significant differences by HIV status.