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. Author manuscript; available in PMC: 2021 Dec 29.
Published in final edited form as: Pediatr Res. 2020 Apr 20;89(3):554–562. doi: 10.1038/s41390-020-0885-7

Table 3:

Results of multivariable linear regression models of immune-mediators with significant associations with baseline 25(OH)D concentrations, race, smoking status, maternal age, or BMI at visit 1. Values are reported as percent change in differences (95% CI) with the specific comparison list. CIs including 0 are non-significant. For example, the coefficient relating baseline 25(OH)D to baseline TGF-β indicates that for a 5-unit increase in baseline 25(OH)D, average baseline TGF-β increased by 6.68%, adjusting for maternal race, smoking status, age and BMI at visit 1. Complete results are presented in Supplemental Table S2 (online).

Baseline Immune-mediators

Covariates TGF-β VEGF IL-10

Baseline 25(OH)D
(5-unit increase)
6.68**
(2.36, 10.8)
0.52
(−7.70, 8.10)
4.45
(−4.21, 12.4)

Race
Black vs. White 7.89
(−12.9, 24.8)
−23.1
(−76.5, 14.2)
25.8
(−9.98, 49.9)
Black vs. Hispanic −13.4
(−38.0, 6.88)
23.1
(−8.90, 45.7)
−21.5
(−77.4, 16.8)
White vs Hispanic −23.1*
(−49.7, −1.21)
37.5**
(11.9, 55.7)
−63.7*
(−138, −12.5)

Smoking status
Current/Former vs. Never 26.9**
(10.7, 40.1)
−55.0*
(−121, −8.65)
42.1**
(14.7, 60.7)

p < 0.10

*

p < 0.05

**

p < 0.01

***

p < 0.001