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. Author manuscript; available in PMC: 2021 Dec 29.
Published in final edited form as: Diabetologia. 2021 Jul 17;64(10):2279–2291. doi: 10.1007/s00125-021-05501-8

Fig. 7.

Fig. 7

NCAM1 co-registers with PrPC primarily in the cell membrane. (a, e, i) PrPC is expressed in non-diabetic, type 1 diabetic INS(+) and type 1 diabetic INS(−) islets. (b, f, j) NCAM1 is highly expressed in the pancreatic islets of non-diabetic, type 1 diabetic INS(+) and type 1 diabetic INS(−) islets. (c, g, k) We found that NCAM1 highly co-registers with PrPC in all three groups as shown in z-stack 3D reconstruction images (d, h, l). Scale bars, 20 μm. ND, non-diabetic; T1D, type 1 diabetic