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. 2021 Dec 28;22:322. doi: 10.1186/s12931-021-01919-1

Table 2.

Demographics and clinical characteristics between the immunotherapy responder and non-responder groups

Characteristics Responder Non-responder Total P-value
No 8 (72.7) 3 (27.3) 11 (100.0)
Age 63.0 (54.5, 73.8) 62.0 (50.0, 62.0) 63.0 (54.0, 74.0) 0.840
Gender 0.491
 Male, n (%) 7 (87.5) 2 (66.7) 9 (81.8)
 Female, n (%) 1 (12.5) 1 (33.3) 2 (18.2)
Smoking history 0.179
 Current or former, n (%) 7 (87.5) 2 (66.7) 9 (81.8)
 Never, n (%) 1 (12.5) 1 (33.3) 2 (18.2)
Pack-years 35.0 (30.0, 40.0) 41.5 (33.0, 41.5) 35.0 (30.0, 45.0) 0.526
Neutrophil–lymphocyte ratio 2.63 (2.13, 4.36) 1.98 (1.86, 1.98) 2.27 (1.98, 3.76) 0.133
PD-L1 ≥ 10% 2 (25.0) 1 (33.3)
PD-L1 < 10% 6 (75.0) 2 (66.7)
Stage 0.361
 I/II/III/IV, n 0/0/4/4 0/0/1/2 0/0/5/6
Pathologic diagnosis 0.661
 Adenocarcinoma, n (%) 6 (75.0) 2 (66.7) 8 (72.7)
 Squamous cell carcinoma, n (%) 2 (25.0) 1 (33.3) 3 (27.3)