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. 2021 Dec 20;13(24):6383. doi: 10.3390/cancers13246383

Table 1.

Top five up-regulated circRNAs in Clone 1 vs. Control based on FC with their associated parental gene (with hypothesised gene function) adapted from Greene et al. [29].

circRNA FC/(p-Value) Parental Gene Parental Gene Function
hsa_circ_0001275 5.8 (p = 0.047) PLCL2 Part of a 23-gene signature, which predicted metastatic lethal prostate cancer outcomes [36].
hsa_circ_0026462 5.7 (p = 0.026) KRT1 Target receptor overexpressed in breast cancer cells [37].
hsa_circ_0033144 5.2 (p = 0.012) BCL11B Methylation occurs in prostate cancer [38].
hsa_circ_0000673 4.2 (p = 0.038) RSL1D1 Associated with an aggressive phenotype and a poor prognosis in patients with prostate cancer [39].
hsa_circ_0000129 3.9 (p = 0.039) VPS72 May have a role in regulating haematopoietic stem cell activity [40].