Table 1.
General characteristics of non-ampullary duodenal carcinomas compared with both ampullary carcinomas and duodenal papillary adenocarcinomas.
| Characteristics | Non-ampullary duodenal carcinoma | Ampullary carcinoma | Duodenal papillary adenocarcinomas | p† | p†† |
|---|---|---|---|---|---|
| (n = 57) | (n = 62) | (n = 69) | |||
| Mean age (years) | 61.3 (59.2–63.4) | 60 (57.9–62.3) | 60.2 (58.1–62.4) | 0.42 | 0.91 |
| Gender | 0.58 | 0.58 | |||
| F | 36 (63.2%) | 36 (58.1%) | 47 (68.1%) | ||
| M | 21 (36.8%) | 26 (41.9%) | 22 (31.9%) | ||
| Tumor size (cm) | 1 | 0.86 | |||
| <3 cm | 32 (56.1%) | 35 (56.5%) | 40 (58%) | ||
| >3 cm | 25 (43.9%) | 27 (43.5%) | 29 (42%) | ||
| Histologic grade | 0.85 | 0.07 | |||
| Well or moderately differentiated | 24 (42.1%) | 28 (45.2%) | 41 (59.4%) | ||
| Low or poorly differentiated | 33 (57.9%) | 34 (54.8) | 28 (40.6%) | ||
| LN status | 0.39 | 0.07 | |||
| Positive | 11 (19.3%) | 17 (27.4%) | 24 (34.8%) | ||
| Negative | 46 (80.7%) | 45 (72.6%) | 45 (65.2%) | ||
| Margin status | 1 | 0.8 | |||
| Negative | 50 (87.8%) | 54 (87.1%) | 59 (85.6%) | ||
| Positive | 7 (12.2%) | 8 (12.9%) | 10 (14.4%) | ||
| Perineural invasion | <0.01 | 1 | |||
| Present | 6 (10.5%) | 28 (45.2%) | 7 (10.1%) | ||
| Not present | 51 (89.5%) | 34 (54.8%) | 62 (89.9%) | ||
| TNM stage | 0.71 | 0.072 | |||
| I to II stage | 31 (54.4%) | 36 (58.1%) | 35 (50.7%) | ||
| III to IV stage | 26 (45.6%) | 26 (41.9%) | 34 (49.3%) | ||
| Surgery procedure | 1 | 0.62 | |||
| Radical resection | 50 (87.7%) | 54 (87.1%) | 58 (84.1%) | ||
| Palliative care | 7 (12.3%) | 8 (12.9%) | 11 (15.9%) | ||
| Adjuvant treatment | 0.86 | 0.28 | |||
| Yes | 28 (49.1%) | 32 (51.6%) | 41 (59.4%) | ||
| No | 29 (50.9%) | 30 (48.4%) | 28 (40.6%) | ||
| CEA | 0.41 | 0.35 | |||
| Normal | 28 (49.1%) | 34 (54.8%) | 39 (56.5%) | ||
| High | 11 (19.3%) | 15 (24.2%) | 16 (23.2%) | ||
| Inconclusive | 18 (31.6%) | 13 (21%) | 14 (20.3%) | ||
| CA-199 | 0.41 | 0.47 | |||
| Normal | 27 (47.4%) | 33 (53.2%) | 37 (53.6%) | ||
| High | 13 (22.8%) | 17 (27.4%) | 18 (26.1%) | ||
| Inconclusive | 17 (29.8%) | 12 (19.4%) | 14 (20.3%) |
F, female; M, male.
† p comparison between non-ampullary duodenal carcinoma and ampullary carcinoma.
†† p comparison between non-ampullary duodenal carcinoma and duodenal papillary adenocarcinomas.