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. 2021 Dec 15;11:795891. doi: 10.3389/fonc.2021.795891

Table 3.

Clinicopathological factors by histopathological phenotype.

Characteristics Intestinal type Gastric type Pancreatobiliary type p p††
  (n = 97) (n = 37) (n = 54)    
Mean age (years) 59.7 (58–61.3) 61.1 (57.8–64.4) 61.6 (59.5–63.8) 0.38 0.18
Gender 0.42 1
F 60 (61.9%) 26 (70.3%) 33 (61.1%)
M 37 (38.1%) 11 (29.7%) 21 (38.9%)
Tumor size (cm) 0.70 0.74
<3 cm 55 (56.7%) 23 (62.2%) 29 (53.7%)
>3 cm 42 (43.3%) 14 (37.8%) 25 (46.3%)
Histologic grade 0.70 0.61
Well or moderately differentiated 46 (42.1%) 19(45.2%) 28 (59.4%)
Low or poorly differentiated 51 (57.9%) 18 (54.8) 26 (40.6%)
LN status 0.11 0.004
Positive 18 (19.3%) 12 (27.4%) 22 (34.8%)
Negative 79 (80.7%) 25 (72.6%) 32 (65.2%)
Margin status 0.15 1
Negative 82 (87.8%) 35 (94.6%) 46 (85.6%)
Positive 15 (12.2%) 2 (5.4%) 8 (14.4%)
Perineural invasion 0.34 0.53
Present 18 (10.5%) 10 (45.2%) 13 (10.1%)
Not present 79 (89.5%) 27 (54.8%) 41 (89.9%)
TNM stage 0.56 0.089
I to II stage 58 (59.8%) 20 (54.1%) 24 (44.4%)
III to IV stage 39 (40.2%) 17 (45.9%) 30 (55.6%)
Surgery procedure 0.02 0.007
Radical resection 91 (93.8%) 29 (78.3%) 42 (77.8%)
Palliative care 6 (6.2%) 8 (21.7%) 12 (22.2%)
Adjuvant treatmen 0.698 0.498
Yes 53 (54.6%) 22 (59.5%) 26 (48.1%)
No 44 (45.4%) 15 (40.5%) 28 (51.9%)

F, female; M, male.

p comparison between non-ampullary duodenal carcinoma and ampullary carcinoma.

††p comparison between non-ampullary duodenal carcinoma and duodenal papillary adenocarcinomas.