Study | Reason for exclusion |
---|---|
Cameron 1985 | Comparison of labetalol with bed rest versus bed rest alone, in hospital. Abstract only. Methods: "randomised". No further information. Participants: 85 pregnant women with hypertension. Intervention: as above. Outcomes: blood pressure, proteinuria, biochemical and haematological tests, tests of placental function, adverse effects of therapy on mother and baby. |
Catalano 1997 | Comparison of nifedipine with bed rest versus bed rest alone, in hospital for women with mild pre‐eclampsia. Methods: "randomly allocated". No further information. Participants: 100 women at 26‐36 weeks' gestation, with mild pre‐eclampsia (not defined in translated summary). Intervention: as above. Outcomes: blood pressure; prolongation of pregnancy; days of hospitalisation; preterm birth; mean birthweight; small‐for‐gestational age. |
Herrera 1993 | Participants: normotensive women. Methods: randomisation by computer‐generated list. Allocation concealment by closed envelopes. Participants: 74 primigravida women at 28‐29 weeks' gestation with normal blood pressure and a positive roll‐over test. Intervention: bed rest at home and nutritional supplements (soy protein, linoleic acid, calcium) versus no bed rest at home and placebo (iron tablets). Outcomes: pregnancy‐induced hypertension; pre‐eclampsia; caesarean section; gestational age at birth; mean birthweight. |
Mathews 1977 | Participants excluded after randomisation if they opted out of the study because they were not happy with allocated treatment. Trialist contacted to determine the number of participants excluded after randomisation, but this information was not available. Methods: participants "allocated at random" to 1 of 4 groups using previously prepared cards contained in envelopes. No further information. Participants: 135 women with singleton pregnancy between 28 to over 38 weeks, with non‐proteinuric hypertension (diastolic BP between 90 and 109 mmHg), and asymptomatic. Intervention: (4 groups) bed rest in hospital with or without sedation (phenobarbitone 15 mg 3 times daily) versus normal activity at home with or without sedation. Outcomes: severe hypertension (BP > 109 mmHg); proteinuria; eclampsia; induction of labour; operative vaginal delivery; caesarean section; biochemical parameters; stillbirths and neonatal death; fetal distress during labour; Apgar score; small for gestation; preterm birth. |
Sibai 1992 | Comparison of nifedipine with bed rest versus bed rest alone, in hospital. Methods: randomised controlled trial. Participants: 200 women at 26‐36 weeks' gestation with proteinuric and non‐proteinuric hypertension. Interventions: as above. Outcomes: blood pressure; haematological and biochemical parameters; days in hospital; prolongation of pregnancy; preterm delivery; gestation at birth; mean birthweight; small‐for‐gestational age; placental weight; cord blood gas. |
Somers 1989 | 3‐arm trial in which all 3 groups of participants had bed rest varying from 15.8 to 18 hours per day along with additional interventions. Methods: "randomly" assigned. No further information. Participants: 45 women at 30‐36 weeks with hypertension, all prescribed restricted physical activity for hypertension. Interventions: 3 arms: bed rest at home versus bed rest and compliance enhancement training at home verus bed rest, compliance enhancement training, and bio‐behavioral interventions at home. Outcomes: mean arterial pressure; compliance with bed rest. |
Spinapolice 1983 | Participants normotensive pregnant women. Methods: "random allocation". No further information available. Participants: 32 nulliparous women at 28‐32 weeks' gestation with a normal blood pressure and positive roll‐over test. Intervention: bed rest for 4 to 6 hours at home versus normal activity at home. Outcomes: gestational hypertension; pre‐eclampsia; gestation at delivery; birthweight; Apgar scores. |
BP: blood pressure