Skip to main content
. 2021 Dec 25;14:7371–7379. doi: 10.2147/JIR.S343125

Table 3.

The Predictive Capacity of Prealbumin, Retinol-Binding Protein 4, CRP and FC for Identifying Endoscopic Remission in the Training Cohort

AUROC (95% CI) Cut-Off Value Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI)
Prealbumin (mg/L) [N= 332] 0.773 (0.705–0.841) 215.5 0.770 (0.642–0.865) 0.697 (0.638–0.751) 0.364 (0.283–0.454) 0.931 (0.885–0.963)
RBP 4 (mg/L) [N= 282] 0.728 (0.646–0.809) 24.8 0.723 (0.571–0.839) 0.702 (0.639–0.759) 0.327 (0.240–0.427) 0.927 (0.876–0.959)
CRP (mg/L) [N= 332] 0.759 (0.693–0.826) 8.7 0.820 (0.696–0.902) 0.587 (0.525–0.646) 0.309 (0.240–0.387) 0.935 (0.884–0.966)
FC (mg/kg) [N= 174] 0.815 (0.727–0.904) 54.5 0.704 (0.497–0.855) 0.844 (0.772–0.896) 0.452 (0.302–0.388) 0.939 (0.880–0.972)
FC+ prealbumin [N= 174] 0.842 (0.775–0.908) 0.107 0.963 (0.791–0.998) 0.646 (0.563–0.722) 0.333 (0.233–0.450) 0.990 (0.935–0.999)

Abbreviations: N, number of available participants; RBP4, retinol-binding protein 4; CRP, C-reactive protein; FC, faecal calprotectin; AUROC, the area under ROC curve; PPV, positive predictive value; NPV, negative predictive value.