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. 2021 Dec 29;11(12):e650. doi: 10.1002/ctm2.650

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© 2021 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Donor‐derived heterogeneity of mesenchymal stem cells (MSCs) across multiple tissues. (A) The proportion of MSC subpopulations in each donor. The colour bar representing clusters with a high proportion (above 5%) and the grey bar encoding the merged clusters (less than 5%). (B) Correlation coefficient heatmap for different donor‐derived MSCs. The correlative value between each two‐individual donor on total differential expressed genes (DEGs). Colour legend (blue to red) encoding the value from 0 to 1. (C) Venn plot showing the overlapping DEGs in ECM associated terms. (D–E) The relative expression of genes within each ECM term: ECM regulators (D), overlapping and specific core matrisome (E). The expression was row‐scaled and coloured by low to high.