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. 2021 Dec 29;11(12):e650. doi: 10.1002/ctm2.650

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© 2021 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Inferred transcriptional factor regulatory networks interpreting inter‐ and intra‐tissue mesenchymal stem cell (MSC) heterogeneity. Regulons are hierarchically clustered based on the activation pattern of transcriptional factors using TRRUST. (A) Venn diagram shows the tissue‐specific and overlapping transcription factors (TFs) by Venny. (B–E) Heatmap shows the p‐value for detailed TFs in intra‐subsets from each tissue. (B) Adipose, (C) Bone marrow, (D) Umbilical cords and (E) Dermis. The colour scale above the heatmap showed a range of –log p‐value. Red, high expression; blue, low expression.