Table 1.
Maternal and study characteristics of exposure by cotinine and THC-COOH
| Cotinine | THC-COOH | |||||
|---|---|---|---|---|---|---|
| Positive | Negative | P-value | Positive | Negative | P-value | |
| N=99 | N=1098 | N=47 | N=1150 | |||
| Maternal age (years) | 26.6 ±5.9 | 27.8 ±5.7 | 0.05 | 26.1 ±6.1 | 27.8 ±5.7 | 0.04 |
| Maternal BMI (kg/m 2 ) | 30.0 ±8.0 | 29.0 ±6.5 | 0.47 | 29.3 ±8.1 | 29.0 ±6.6 | 0.65 |
| Education | <0.001 | 0.003 | ||||
| Less than high school |
33 (33) | 498 (45) | 20 (43) | 511 (44) | ||
| High school | 61 (62) | 354 (32) | 25 (53) | 390 (34) | ||
| College | 5 (5) | 246 (22) | 2 (4) | 249 (22) | ||
| Married/partner | 41 (41) | 838 (76) | <0.001 | 21 (45) | 858 (75) | <0.001 |
| Private insurance | 13 (13) | 325 (30) | <0.001 | 3 (6) | 335 (29) | <0.001 |
| Race or ethnicity | <0.001 | <0.001 | ||||
| Black | 41 (41) | 136 (12) | 21 (45) | 156 (14) | ||
| Hispanic | 11 (11) | 621 (57) | 5 (11) | 627 (55) | ||
| Other* | 2 (2) | 23 (2) | 2 (4) | 23 (2) | ||
| White | 45 (46) | 318 (29) | 19 (40) | 344 (30) | ||
| Gestational age at randomization & urine sample (weeks) | 17.4 ± 3.0 | 17.1 ±3.0 | 0.21 | 17.5 ±2.9 | 17.1 ±3.0 | 0.34 |
| Gestational age at delivery (weeks) | 38.1 ±4.7 | 39.0 ±2.6 | 0.42 | 38.5 ±4.4 | 39.0 ±2.7 | 0.30 |
| Levothyroxine Treatment group | 47 (48) | 554 (51) | 0.57 | 25 (53) | 576 (50) | 0.68 |
| Thyroid status | <0.001 | <0.001 | ||||
| Subclinical hypothyroxinemia | 27 (27) | 647 (59) | 9 (19) | 665 (58) | ||
| Subclinical hypothyroidism | 72 (73) | 451 (41) | 38 (81) | 485 (42) | ||
*
Includes Asian, American Indian and participant-selected “other” category for race.