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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Curr Hematol Malig Rep. 2021 Mar 17;16(2):183–191. doi: 10.1007/s11899-021-00624-6

Table 1:

Selected Monoclonal Antibodies Investigated in Clinical Trials in Multiple Myeloma

Agent Target Clinical Trial Phase Single vs combination
CJM112 IL-17 NCT03111992 I Single/combination (Anti-PD1 or SMAC-mimetic)
BHQ880 DKK-1 NCT01302886, NCT01337752 II Single/combination (bor and dex)
Lirilumab KIR NCT02252263 I With elotuzumab
MOR202/TJ202 CD38 NCT01421186 I/II With dex and len/pom
NCT03860038 II With dex
NCT03952091 III With len and dex
TAK-079 CD38 NCT03439280 I/II Single/combination (pom/dex)
TAK-573 CD38 NCT03215030 I/II Single (phase I)
With dex (phase II)
SEA-BCMA BCMA NCT03582033 I With dex

Bor: bortezomib, len: lenalidomide, pom: pomalidomide, dex: dexamethasone