Table 1:
Agent | Target | Clinical Trial | Phase | Single vs combination |
---|---|---|---|---|
CJM112 | IL-17 | NCT03111992 | I | Single/combination (Anti-PD1 or SMAC-mimetic) |
BHQ880 | DKK-1 | NCT01302886, NCT01337752 | II | Single/combination (bor and dex) |
Lirilumab | KIR | NCT02252263 | I | With elotuzumab |
MOR202/TJ202 | CD38 | |||
NCT03952091 | III | With len and dex | ||
TAK-079 | CD38 | NCT03439280 | I/II | Single/combination (pom/dex) |
TAK-573 | CD38 | NCT03215030 | I/II | Single (phase I) With dex (phase II) |
SEA-BCMA | BCMA | NCT03582033 | I | With dex |
Bor: bortezomib, len: lenalidomide, pom: pomalidomide, dex: dexamethasone