Figure 4. Model predictions reproduce reversible inhibition of root growth by externally applied auxin.
(A) Successive application of external auxin in model simulations according to a predefined cycle. Root growth is inhibited by the introduction of high amounts of auxin and subsequently restored after the external application is stopped as seen in experiments (Fendrych et al., 2018). (B) Schematic of the in silico experiment. To simulate auxin treatment as described in Fendrych et al., 2018, we introduced external auxin inside the root (by inducing excessive auxin synthesis at individual cell level) at predefined time points to inhibit root growth and subsequently removed to allow root growth re-establishment. (C) Time-lapse profile of root growth rate (red line) and average cell auxin concentrations (blue line). The cycles of external auxin applications inhibit and restore root growth, respectively. The simulation has been run for 1500 time steps.
Figure 4—figure supplement 1. The reversible inhibition of root growth by external auxin applications.
