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Structure of the spike glycoprotein and mutations information. (a) Domain organization of spike glycoprotein and representation of RBD domain. (b) The predicted mutations' scores by mCSM-PPI2. (c) Represent the intra and inter residues bonding network of wild type while (d) (e) and (f) represent the intra and inter residues bonding network of the three mutants N501I, N501T and N501V.
