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Evaluation of assay specificity of the dual-mode SERS-based aptasensor. (a) Normalized average Raman spectra for blank, SARS-CoV-2 (200 PFU/mL), influenza A/H3N2 (1000 HAU/mL), influenza A /H1N1 (80 HAU/mL), and influenza B (500 HAU/mL). (b) Corresponding histograms for the normalized Raman peak intensity ratios (I1470/I1075) and (I1650/I1075) collected from the SERS peak intensities in (a).
