Table 8.
Cytotoxic effect of ligand acids and complexes on malignant glioma U-87 cell lines.a
| Compound | Survival fraction (%) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Dose Conc. (µg/mL) | ||||||||
| 0 | 7.812 | 15.625 | 31.25 | 62.5 | 125 | 250 | 500 | |
| HL1 | 100 | 75.74 ± 0.06 | 50.70 ± 0.04 | 36.66 ± 0.04 | 23.84 ± 0.02 | 15.69 ± 0.01 | 16.98 ± 0.00 | 19.92 ± 0.01 |
| HL2 | 100 | 83.84 ± 0.09 | 58.94 ± 0.04 | 37.29 ± 0.04 | 20.34 ± 0.03 | 15.51 ± 0.01 | 15.04 ± 0.02 | 18.97 ± 0.05 |
| 1 | 100 | 84.13 ± 0.09 | 60.27 ± 0.04 | 45.09 ± 0.03 | 25.05 ± 0.03 | 20.92 ± 0.03 | 17.52 ± 0.02 | 61.44 ± 0.21 |
| 2 | 100 | 82.28 ± 0.02 | 49.55 ± 0.11 | 34.02 ± 0.07 | 19.41 ± 0.02 | 15.86 ± 0,02 | 14.21 ± 0.01 | 54.65 ± 0.18 |
a = The cell lines were treated with different concentrations of the test compounds in vitro for 24 h.