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. 2021 Dec 16;12:778204. doi: 10.3389/fimmu.2021.778204

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Copyright © 2021 Aliaga-Gaspar, Hurtado-Guerrero, Ciano-Petersen, Urbaneja, Brichette-Mieg, Reyes, Rodriguez-Bada, Alvarez-Lafuente, Arroyo, Quintana, Ramió-Torrentà, Alonso, Leyva, Fernández and Oliver-Martos

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Longitudinal assessment of IFNAR1, IFNAR2, sIFNAR2 and MxA gene expression in responder and non-responder patients. (A) Heat map representing the gene expression data of IFNAR1, IFNAR2, sIFNAR2, and MxA between responder and non-responder patients, at baseline and 6 months after the onset of IFN-β therapy. Unchanged proteins are displayed in black, up-regulated proteins are displayed in green while the down-regulated proteins are depicted in red. (B) Bar chart representing the gene expression for responders (N=22) and non-responders (N=19) using GAPDH as raeference gene. Significant p-values are shown with asterisk.