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. 2021 Dec 16;12:799206. doi: 10.3389/fimmu.2021.799206

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Copyright © 2021 Zhang, Li, Cao, Wang, Xie, Li, Wang, Guo, Jiang and Guo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression patterns of solid tumor antigens (GPC3, B4GALNT1, and ERBB2) in human normal tissues and organs. (A) GPC3 and ERBB2-expressing proportions (expression value >0) of PBMC-derived cells. (B) Violin plots show the expression levels of GPC3, B4GALNT1, and ERBB2 in heart-derived clusters and ascending aortic tissue-derived cells. GPC3, B4GALNT1, and ERBB2-expressing proportions (expression value >0) of lung-derived cells (C), kidney-derived cells (D), and pancreas-derived cells (E). (F) UMAP plots show the expression level of ERBB2 in small intestine-derived cells and rectum-derived cells. (G) UMAP plots show the expression levels of GPC3, B4GALNT1, and ERBB2, in skin-derived clusters. (H) Schematic diagram of high GPC3/B4GALNT1/ERBB2-expressing cell types in different tissues and organs.