Table 5A.
Detection of cellular responses against HER2 after vaccination.
| Patients | IFNγ | Granzyme B | TNF-α | Summary of post-vaccination anti-HER2 response | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ECD | ICD | ECD | ICD | ECD | ICD | ECD | ICD | ECD/ICD | ||||||||||
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Vaccination response | Induced response only | Vaccination response | Induced response only | Induced response only | ||
| 18 | Adjuvant | + | + | − | − | + | + | − | + | + | + | − | − | + | − | + | + | + |
| 20 | Adjuvant | + | + | − | + | + | + | − | − | − | + | − | − | + | + | + | + | + |
| 17 | CR* | − | + | − | − | − | + | − | − | − | + | − | − | + | + | − | − | + |
| 9 | PR* | − | + | + | + | − | + | − | + | − | + | − | + | + | + | + | + | + |
| 21 | SD* | − | − | − | − | − | + | − | − | − | − | − | − | + | + | − | − | + |
| 11 | SD | + | − | + | − | − | − | − | + | + | − | − | − | − | − | + | + | + |
| 12 | SD | + | − | − | − | − | + | − | − | − | + | − | − | + | + | − | − | + |
| 25 | SD | + | + | − | − | − | − | − | − | − | − | − | − | + | − | − | − | − |
| 16 | PD | − | − | − | − | + | + | + | − | + | + | − | + | + | − | + | + | + |
| 26 | PD | − | + | − | + | − | − | − | + | + | − | + | + | + | + | + | + | + |
| 27 | PD | + | + | − | + | − | + | + | + | + | + | + | + | + | + | + | + | + |
| Total | 6 | 7 | 2 | 4 | 3 | 8 | 2 | 5 | 5 | 7 | 2 | 4 | 10 | 7 | 7 | 7 | 10 | |