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(A) Representative mIPSCs from CeA neurons during control and during superfusion with the KOR-agonist U-50488 (1 μM, upper panel) or the KOR-antagonist norBNI (200 nM, lower panel) are shown. Bars represent means ± S.E.M of the normalized effects either (B) U-50488 or (C) norBNI at the indicated concentration on mIPSC characteristics. Statistically significant differences to baseline control were calculated using a one-sample t-test. (*) = P < 0.05, (***) = P < 0.001.
