Table 1.
Patient | Sex | Age | Epilepsy | AED | Sleep disorder treatment | DIMS | SBD | AD | SWTD | DOES | SHY | TOTAL |
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. 1 | F | 1y | Yes | No therapy | – | 41 | 51 | 47 | 50 | 46 | 51 | 45 |
No. 2 | F | 1y | No | – | – | 60 | 45 | 47 | 75 | 42 | 69 | 62 |
No. 3 | F | 1y, 5m | No | – | – | 64 | 51 | 47 | 66 | 64 | 45 | 64 |
No. 4 | M | 1y, 5m | No | – | – | 73 | 86 | 47 | 41 | 64 | 64 | 70 |
No. 5 | M | 2y, 4m | Yes | VGB, VPA | Melatonin | 79 | 100 | 70 | 84 | 81 | 69 | 99 |
No. 6 | F | 6y | No | – | Melatonin | 66 | 100 | 94 | 100 | 69 | 69 | 100 |
No. 7 | M | 7y, 3m | Yes | CBZ | – | 70 | 100 | 100 | 75 | 73 | 45 | 90 |
No. 8 | F | 11y 6m | Yes | VPA | – | 60 | 45 | 70 | 58 | 88 | 45 | 69 |
No. 9 | F | 11y, 10m | No | N/A | – | 60 | 45 | 70 | 41 | 50 | 45 | 51 |
No. 10 | F | 12y, 1m | Yes | CBZ | – | 70 | 86 | 47 | 41 | 53 | 45 | 62 |
No. 11 | F | 13y, 7m | Yes | VPA, CBZ | – | 64 | 58 | 58 | 79 | 58 | 45 | 68 |
No. 12 | M | 14y, 4m | No | – | – | 66 | 58 | 70 | 58 | 50 | 45 | 62 |
No. 13 | M | 16y, 4m | Yes | PB, LEV, VGB, CBZ | – | 100 | 100 | 70 | 41 | 77 | 69 | 100 |
No. 14 | M | 17y, 4m | Yes | LEV, CBZ | Melatonin | 73 | 86 | 47 | 50 | 42 | 45 | 62 |
MEDIAN (IQR) | 66 (11.25) | 72 (45.5) | 64 (23) | 58 (31.75) | 61 (22) | 45 (22.75) | 66 (23) |
AED, anti–epileptic drugs; VPA, valproic acid; VGB, vigabatrin; CBZ, carbamazepine; PB, phenobarbital; LEV, levetiracetam. For all patients, the melatonin dosage ranged from 2 to 5 mg.