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. 2021 Dec 16;12:774443. doi: 10.3389/fneur.2021.774443

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Copyright © 2021 Wang, Ke, Wang, Wu, Zhou, Tan, Liu, Geng, Cheng, Liu, Yu, Song, Qiu, Li, Luo, Yang, Zi, Wang and Yuan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subgroup analyses of primary outcomes. The forest plot shows the differences in odds ratios for favorable outcomes (defined as modified Rankin Scale score of 0–3) at 3 months in the prespecified subgroups. Adjusted variables: age, National Institutes of Health Stroke Scale (NIHSS), onset to imaging time, occlusion site, posterior circulation collateral system score (PC-CS), posterior circulation Alberta Stroke Program Early CT Score (pc-ASPECTS). IVT, intravenous thrombolysis; OTI, onset to imaging diagnosis time.